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Souvik Bhattacharjee

Souvik Bhattacharjee

Souvik Bhattacharjee
Souvik Bhattacharjee
Associate Professor
Centre/School/Special Centre
Special Centre for Molecular Medicine
Room No
3D (FF)
Off. Phone
011-26738974
Email
souvik@jnu.ac.in, sbh174@gmail.com
Personal Webpage
http://www.jnu.ac.in
Qualifications

2004: Ph.D. Institute of Microbial Technology, Chandigarh, India. 
1997: M.Sc. Biotechnology. Madurai Kamaraj University, Madurai, India. 
1995: B.Sc. (Honors) Biochemistry, Delhi University. 

Areas of Interest/Specialization

Infectious diseases in plants and animals, Malaria, Protein trafficking, artemisinin resistance

Experience
Associate Professor, Special Centre for Molecular Medicine, Jawaharlal Nehru University, New Delhi, India. July 2015-present. Research Assistant Professor, Center for Rare and Neglected Diseases, Department of Biological Sciences, University of Notre Dame, Notre Dame, Indiana. 2010 – 2015. Research Associate, Laboratory of Prof. Kasturi Haldar, Center for Rare and Neglected Diseases, Department of Biological Sciences, University of Notre Dame, Notre Dame, Indiana. 2008 - 2010. Post-doctoral fellow, Laboratory of Prof. Kasturi Haldar, Department of Pathology, Feinberg School of Medicine, Northwestern University, Chicago. 2004 - 2008.
Awards & Honours

2007: Travel Grant awarded by the Center for Genetic Medicine, Northwestern University to attend Gordon Red Cell Meeting (GCM) at Aussois, France.
2004: Northwestern University award for Best Poster presentation at the Department of Pathology, Chicago.
1999-2002: CSIR/UGC National Eligibility Test Senior Research Fellowship (SRF). Government of India.
1997-1999: CSIR/UGC National Eligibility Test Junior Research Fellowship (JRF). Government of India.
1995-1997: M. Sc. Biotechnology Fellowship from the Department of Biotechnology (DBT), Ministry of Science and Technology, Government of India. 

International Collaboration/Consultancy

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Best Peer Reviewed Publications

Hari Madhav, Tarosh S. Patel, Zeba Rizvi, G. Srinivas Reddy, Abdur Rahman, Md. Ataur Rahman, Saiema Ahmedi, Sadaf Fatima, Kanika Saxena, Nikhat Manzoor, Souvik Bhattacharjee, Bharat C. Dixit, Puran Singh Sijwali, Nasimul Hoda. Development of diphenylmethylpiperazine hybrids of chloroquinoline and triazolopyrimidine using Petasis reaction as new cysteine proteases inhibitors for malaria therapeutics. European Journal of Medicinal Chemistry. Volume 258, 5 October 2023, 115564.

Pal K, Raza Md. K, Legac J, Rahman A, Manzoor S, Bhattacharjee S, Rosenthal PJ and Hoda N. Identification, in-vitro anti-plasmodial assessment and docking studies of series of tetrahydrobenzothieno[2,3-d]pyrimidine-acetamide molecular hybrids as potential antimalarial agents. European Journal of Medicinal Chemistry. Volume 248, 15 February 2023, 115055

Chaurasiya A, Kumari G, Garg S, Shoaib R, Anam Z, Joshi N, Kumari J, Singhal J, Singh N, Kaushik S, Kahlon AK, Dubey N, Maurya MK, Srivastava P, Marothia M, Joshi P, Gupta K, Saini S, Das G, Bhattacharjee S, Singh S, Ranganathan A. Targeting Artemisinin-Resistant Malaria by Repurposing the Anti-Hepatitis C Virus Drug Alisporivir. Antimicrob Agents Chemother. 2022 Dec 20;66(12): e0039222. doi: 10.1128/aac.00392-22. Epub 2022 Nov 14. PMID: 36374050

Goel N, Dhiman K, Kalidas N, Mukhopadhyay A, Ashish F, Bhattacharjee S. Plasmodium falciparum Kelch13 and its artemisinin-resistant mutants assemble as hexamers in solution: a SAXS data-driven modelling study. FEBS J. 2022 Jan 28. doi: 10.1111/febs.16378. Online ahead of print. PMID: 35092154.

Kumar T, Maitra S, Rahman A, Bhattacharjee S. A conserved guided entry of tail-anchored pathway is involved in the trafficking of a subset of membrane proteins in Plasmodium falciparum. PLoS Pathog. 2021 Nov 15;17(11): e1009595. doi: 10.1371/journal.ppat.1009595.

Nayak A, Saxena H, Bathula C, Kumar T, Bhattacharjee S, Sen S and Gupta A. Diversity‑oriented synthesis derived indole based spiro and fused small molecules kills artemisinin‑resistant Plasmodium falciparum. Malar J (2021) 20:100. https://doi.org/10.1186/s12936-021-03632-2.

Kannan D, Yadav N, Ahmad S, Namdev P, Bhattacharjee S, Lochab B and Singh S. Pre-clinical study of iron oxide nanoparticles fortified artesunate for efficient targeting of malarial parasite. EBioMedicine. 2019 Jul; 45:261-277. doi: 10.1016/j.ebiom.2019.06.026.

Bhattacharjee S, Coppens I, Mbengue A, Suresh N, Ghorbal M, Slouka Z, Safeukui I, Tang HY, Speicher DW, Stahelin RV, Mohandas N, Haldar K. Remodeling of the malaria parasite and host human red cell by vesicle amplification that induces artemisinin resistance. Blood. 2018 Mar 15;131(11):1234-1247.

Haldar K, Bhattacharjee S, Safeukui I. Drug resistance in Plasmodium. Nat Rev Microbiol. 2018 Mar;16(3):156-170. doi: 10.1038/nrmicro.2017.161. Epub 2018 Jan 22. Review.

Alassane Mbengue, Souvik Bhattacharjee*, Trupti Pandharkar, Haining Liu, Guillermina Estiu, Robert V. Stahelin, Shahir Rizk, Dieudonne L. Njimoh, Yana Ryan, Kesinee Chotivanich, Chea Nguon, Mehdi Ghorbal, Jose-Juan Lopez-Rubio, Michael Pfrender , Scott Emrich, Narla Mohandas, Arjen M. Dondorp, Olaf Wiest and Kasturi Haldar. A molecular mechanism of artemisinin resistance in Plasmodium falciparum malaria. Nature 520, 683–687 (30 April 2015).

Total Published Research Articles in National/International Journals: 29

Total Published Abstracts in National/International Journals: 15

Recent Peer Reviewed Journals/Books

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Patents (if any)
‘Compositions and Methods for treatment, research and therapeutic applications for malaria. Filed on 10/22/2008. US Patent No. 8,465,746, Issued: June 18th, 2013. (Inventors: Kasturi Haldar, Pamela Tamez and Souvik Bhattacharjee, Notre Dame, IN. Assignee: Northwestern University, 633 Clark Street, Evanston, IL 60208). 

A warm welcome to the modified and updated website of the Centre for East Asian Studies. The East Asian region has been at the forefront of several path-breaking changes since 1970s beginning with the redefining the development architecture with its State-led development model besides emerging as a major region in the global politics and a key hub of the sophisticated technologies. The Centre is one of the thirteen Centres of the School of International Studies, Jawaharlal Nehru University, New Delhi that provides a holistic understanding of the region.

Initially, established as a Centre for Chinese and Japanese Studies, it subsequently grew to include Korean Studies as well. At present there are eight faculty members in the Centre. Several distinguished faculty who have now retired include the late Prof. Gargi Dutt, Prof. P.A.N. Murthy, Prof. G.P. Deshpande, Dr. Nranarayan Das, Prof. R.R. Krishnan and Prof. K.V. Kesavan. Besides, Dr. Madhu Bhalla served at the Centre in Chinese Studies Programme during 1994-2006. In addition, Ms. Kamlesh Jain and Dr. M. M. Kunju served the Centre as the Documentation Officers in Chinese and Japanese Studies respectively.

The academic curriculum covers both modern and contemporary facets of East Asia as each scholar specializes in an area of his/her interest in the region. The integrated course involves two semesters of classes at the M. Phil programme and a dissertation for the M. Phil and a thesis for Ph. D programme respectively. The central objective is to impart an interdisciplinary knowledge and understanding of history, foreign policy, government and politics, society and culture and political economy of the respective areas. Students can explore new and emerging themes such as East Asian regionalism, the evolving East Asian Community, the rise of China, resurgence of Japan and the prospects for reunification of the Korean peninsula. Additionally, the Centre lays great emphasis on the building of language skills. The background of scholars includes mostly from the social science disciplines; History, Political Science, Economics, Sociology, International Relations and language.

Several students of the centre have been recipients of prestigious research fellowships awarded by Japan Foundation, Mombusho (Ministry of Education, Government of Japan), Saburo Okita Memorial Fellowship, Nippon Foundation, Korea Foundation, Nehru Memorial Fellowship, and Fellowship from the Chinese and Taiwanese Governments. Besides, students from Japan receive fellowship from the Indian Council of Cultural Relations.